Lanluma (PLLA)

Lanluma, a biostimulatory filler composed of poly-L-lactic acid (PLLA), is increasingly used not only for facial aesthetic improvements but also for non-surgical body rejuvenation. Its long-lasting effects, high patient satisfaction, and excellent safety profile make it a top choice for treating a range of aesthetic concerns, including volume loss, skin laxity, cellulite, stretch marks, and wrinkles.

As demand rises for minimally invasive cosmetic treatments that improve appearance without surgery, both women and men are turning to PLLA fillers like Lanluma to maintain and enhance a youthful look.

What Is Lanluma Filler Made Of?

Lanluma is an injectable collagen stimulator that uses poly-L-lactic acid (PLLA)—a biodegradable, biocompatible polymer that has been used safely in medicine for over 30 years. It is formulated as a sterile powder and diluted with sterile water before injection.

Once injected, Lanluma stimulates the body’s natural collagen production and gradually restores volume over time. Unlike hyaluronic acid (HA) fillers, which provide immediate volume, PLLA-based fillers trigger long-term skin remodeling through neocollagenesis.

Where Has PLLA Been Used Before?

PLLA has a long history of medical use in sutures and orthopedic applications. In aesthetic medicine, its use began in Europe in 1999 and in the United States in 2009. While the earlier PLLA filler Sculptra is primarily approved for facial use, Lanluma is approved for both facial and body indications.

Lanluma is available in two formulations:

• Lanluma V (210 mg per vial) – used for facial areas.
• Lanluma X (630 mg per vial) – used for larger body areas such as the buttocks.

How Does Poly-L-lactic Acid (PLLA) Filler Work?

Once reconstituted and injected, Lanluma PLLA acts as a biostimulatory agent. The PLLA microparticles gradually stimulate Type I collagen production, improving skin texture, volume, and elasticity over the course of several months.

Key distinctions between PLLA fillers like Lanluma and other fillers such as HA, PCL (Ellansé), or calcium hydroxyapatite (Radiesse) include:

• Delayed but long-lasting results
• Collagen stimulation vs. immediate filling
• Greater suitability for large-volume body contouring

Areas of Application: Where Can Lanluma Be Used?

Lanluma is indicated for use in a wide range of treatment areas:

Face:

• Volume loss
• Nasolabial folds, marionette lines
• Mid-face contouring
• Skin laxity and wrinkles

Neck & Décolletage:

• Crepey skin
• Horizontal neck lines
• Wrinkle correction
• Long-lasting collagen stimulation

PLLA Butt Filler: Non-Surgical BBL with Poly-L-lactic Acid:

• Buttock augmentation
• Improved contour and shape
• Skin quality enhancement
• Reduction in visible cellulite
• Popular alternative to fat grafting and implants, especially for slim patients

Abdomen:

• Mild to moderate skin laxity
• Postpartum or post-weight-loss rejuvenation
• Improved skin quality and tightness

Arms:

• Sagging inner upper arms (“bat wings”)
• Enhanced firmness and tone

Thighs:

• Cellulite and skin laxity
• Inner and outer thigh reshaping

Knees:

• Loose skin above knees
• Restores firmness and reduces wrinkles

Hands:

• Volume loss and visible tendons
• Aging signs and sun damage
• Improves density and softness of the skin

What to Expect During and After Treatment

• Preparation: The powder is mixed with sterile water and shaken for at least 2 hours before injection.
• Injection: Administered with a cannula to the subdermal layer using fanning or linear threading technique.
• Schedule: Typically 3 sessions spaced 4 weeks apart.
• Onset: Initial volume may appear within 48 hours due to water retention; true collagen-based results appear within 3–6 months.
• Duration: Effects last up to 2 years after a full course.

Benefits of Lanluma (PLLA)

• Stimulates the body’s natural collagen for gradual and lasting rejuvenation
• Ideal for both face and body applications
• Non-surgical solution for buttock lifting, contouring, and cellulite improvement
• Safe for use in large volumes without the risks of surgery
• Clinically proven safety and high patient satisfaction rates
• Minimal downtime with natural-looking results

Is Lanluma Safe?

Yes. Lanluma has demonstrated an excellent safety profile in clinical studies and real-world practice. Side effects are usually mild and temporary, including:

• Swelling
• Bruising
• Tenderness at the injection site

Rare complications may include:

• Asymmetry
• Lumps or nodules
• Infection (rare)
• Vascular compromise (extremely rare)

Proper injection technique and physician experience significantly reduce the risk of adverse effects.

Lanluma vs. Hyaluronic Acid Fillers

Is Lanluma Effective for Cellulite?

Yes. Lanluma X is highly effective in reducing cellulite, especially in the buttocks, hips, and arms. By stimulating collagen, it fills structural voids under the skin and improves overall skin texture and firmness. A treatment plan of 3–6 sessions at 4-week intervals is generally recommended based on cellulite grade and area.

How Much Does Lanluma Cost?

Lanluma is priced based on the number of vials used rather than the treatment area. The cost varies according to:

• Treatment area (face vs. body)
• Volume required (Lanluma V vs. X)
• Number of sessions (typically 1–3)
• Physician expertise

Final Thoughts: Why Choose Lanluma?

As the demand for non-surgical aesthetic solutions continues to grow, Lanluma PLLA filler offers a scientifically backed, safe, and effective method for face and body rejuvenation. Whether you’re seeking to restore lost volume, improve skin texture, or achieve a non-surgical BBL, Lanluma stands out as a top-tier solution backed by decades of medical use and global patient satisfaction.